I can get you to where it wouldn't be hellish, and it's all a good part of town. Once into St. Louis you would be taking I-44 to get through. take I-44 to South onto Hampton Ave. About a half mile on the right, make a right onto Watson Rd. Take that about a mile and merge right onto Chippewa and Ted Drewes will be a few blocks on the left.
Then you could either keep going on Chippewa which will turn into Watson again and that will run you right into W I-44 several miles down. Like I said it's all a nice area and it's not typically heavy traffic. Or after leaving Ted Drewes, you could make a right at the next stop light onto Jamieson Ave. and take that about a mile back up to I-44.
Anyway, if you have any questions about this area when you're ready to go, let me know. I'll help you any way I can.